To post the answer to my question (courtesy of iDC at OSX Hints)
Install the Prolific 1.0.7b4 drivers.
Log in as root and use Text Edit to open the Info.plist in the ProlificUsbSerial.kext in the path
System/Library/Extensions.
In the Info.plist find the line
<key>IOKitPersonalities</key>
<dict>
and paste in the following after the <dict> tag:
--------Start paste
<key>5003_056E</key>
<dict>
<key>CFBundleIdentifier</key>
<string>com.prolific.driver.PL2303</string>
<key>IOClass</key>
<string>com_prolific_driver_PL2303</string>
<key>IOProviderClass</key>
<string>IOUSBInterface</string>
<key>bConfigurationValue</key>
<integer>1</integer>
<key>bInterfaceNumber</key>
<integer>0</integer>
<key>idProduct</key>
<integer>20483</integer>
<key>idVendor</key>
<integer>1390</integer>
--------End paste
Save the change and reboot with the UC-SGT plugged into the keyboard, etc.
The message that a new usbserial device has been found should be displayed.
That's it.