I just installed one of these (F5U220) in my desktop Mac running OS X Panther 10.3.5, and it works unevenly. For example, I have my keyboard attached to it and although the keys work fine, the startup button doesn't function (it works fine using the built-in USB 1.1 ports).
This prompts me to ask, what is the status of USB 2.0 support in Panther? Do I need a third-party driver to achieve full functionality?