Yes - any burner compatible with Toast can do this.
With Toast 4 Deluxe, simply burn in either "Files and Folders" mode, for a disc which can be read by both Macs and PC's.
Or, you can burn a Mac/ISO hybrid disc which holds seperate data for Macs and PC's, and only one (sometimes both) will be shown depending on the computer reading it. Also there is an ISO/9660 mode for PC's.
Cipher13