Yes, if you use the Merom model, that is Core 2 Duo for mobiles, model number 5000 something or 7000 something, for socket M. DO NOT use the cheaper desktop Conroe models, number 4000 something or 6000 something, for socket LGA 775 - they won't fit. Should not cause any heat problems, the TDP is similar (35W compared to 25W)