At the point when the machines were released, the largest available module was 2 gb, so with 8 banks, that's 16 max. Apparently, now there's 4 gb modules available. I have no idea whether a Mac Pro would recognize all 32 gb, but if OWC says it works, I'd figure it to be true, as generally, they seem to know what they're talking about, there. Give 'em a call and ask -- they actually answer the phones there (one of the reasons I buy from them).