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There isn't a system option to disable the function keys. But they're really seldom used for anything on the Mac. I use the brightness and sound keys a lot, and the function keys--never.
No, you're not blind-- It's not built in. The only way that I know of is the already-mentioned uControl. While I can understand why people wouldn't want to use it (risky), I've been using it for about 5 months now without any problems.