Had a BookEndz dock both with my old Wallstreet and my current TiBook.
I work a lot at my desk/work station and when I had lots of peripherals, I wouldn't have wanted to be without one. Also, having a dock meant that I wasn't yanking connections out in a hurry and damaging the pins.
But, once I got Airport and had wireless ethernet and wireless printing, that was the tipping point. Also, I stopped routinely keeping my FW drives plugged in after the Panther FW bug.
So now, I don't mind plugging in my monitor, a USB plug and the power cord.
But again, if you've got lots of peripherals you use every day, it is very convenient.
Keep in mind though, that not only do you have to dismount all drives (which, as noted, is standard OS 10 practice) but BookEndz recommends that you shut down, now just sleep, your PB when docking and undocking.