Hey ucx
I'm running a Toshiba 80gb w/16mb cache on my Pismo. Haven't have any problems. Tried a Fujitsu 80gb, but returned it because it formatted every low compared to the Toshiba...
I'm going to a Toshiba 60gb, 7200rpm drive in my Pismo now. A friend of mine has one in his Pismo, Booting is much faster, program loading, and running is also faster.
Have a Great one!!!
Brad