I believe the iSight has had problems when daisy chained with FW harddrives. Not sure about that though. As for general "overloading" the firewire bus, I think you should be ok. From what I've gathered, two fast, daisy chained hdds might "saturate" your firewire bus (as in, they won't be fast as usual) but there should be no functional problems, just probably a little slow down in speed.