A true clone should work, but it has to be a 100% exact clone. Be careful of what software you use to do the job. I think PowerQuest's (now a Norton product) DriveImage will do the job for you.
Keep in mind that the MacBook uses a SATA drive, so you need the correct adapter in your PC to plug it into. Fortunately, notebook SATA drives use the same connectors that desktop SATA drives do, so they're pretty much interchangeable!