I have a brand-new MacBook Pro (mid-2010) with the high-res antiglare screen. I was using it at home in closed-clamshell mode with a 23" Apple Cinema Display, put it to sleep, and when I later woke it up (at work), the display looked like this:

:
I checked the ColorSync profile while this was happening, and it was fine. Putting the MBP to sleep and waking it again didn't help the problem. Rebooting fixed the problem.
Is this indicative of video problems?