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You are here: MacNN Forums > Community > Team MacNN > Folding at Home Protein Design Engine

Folding at Home Protein Design Engine
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Join Date: Nov 2003
Location: Minnesota
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Dec 2, 2003, 05:44 PM
 
Has anyone seen this before? My client (running on Linux) spit out the following:

Code:
[12:52:29] Verifying core Core_ca.fah... [12:52:29] Signature is VALID [12:52:29] Created: Wednesday April 10, 2002 00:01:22 UTC [12:52:29] Signed: Monday March 3, 2003 00:18:10 UTC [12:52:29] [12:52:29] Trying to unzip core FahCore_ca.exe [12:52:29] Decompressed FahCore_ca.exe (2057360 bytes) successfully [12:52:29] + Core successfully engaged [12:52:35] [12:52:35] + Processing work unit [12:52:35] Core required: FahCore_ca.exe [12:52:35] Core found. [12:52:35] Working on Unit 07 [December 2 12:52:35] [12:52:35] + Working ... [12:52:35] Folding@home Protein Design Core Version 2.06 (Feb 25, 2003) [12:52:35] [12:52:35] Proj: work/wudata_07 [12:52:35] Finding work files [12:52:35] sizeof(CORE_PACKET_HDR) = 512 [12:52:35] Checking frame files [12:52:35] - Couldn't open work/wudata_07.chk [12:52:35] Starting from initial work packet [12:52:35] [12:52:35] Updating shared core-client information [12:52:35] - Writing "work/wudata_07.key": (overwrite)successful. [12:52:35] Key file to update shared file: work/wudata_07.key [12:52:35] keyfile: 0 146 200 15 2 1 0 [12:52:35] Protein: Des2/pdb1ch4.39.spa [12:52:35] - Frames Completed: 0, Remaining: 600 [12:52:35] - Dynamic steps required: 120000 [12:52:35] [12:52:36] Printed current.prm [12:52:36] Writing local files: [12:52:36] - Writing "work/wudata_07.key": (overwrite)successful. [12:52:36] - Writing "work/wudata_07.xyz": (overwrite)successful. [12:52:37] - Writing "work/wudata_07.prm": (overwrite)successful. [12:52:37] Starting design engine [12:52:37] [SPG] project name: work/wudata_07. [12:52:37] [SPG] 1 0 [12:52:37] [SPG] Initializing protein design engine [12:52:37] [SPG] seed = 0 [12:52:37] [SPG] Initialization complete [12:52:37] [SPG] Writing current.pdb, chainlength = 146 [12:52:37] [SPG] Writing current.xyz [12:52:38] [SPG] Preprocessing . . . [12:52:38] [SPG] 146 positions in protein [13:00:53] [SPG] Preprocessing complete [13:00:53] Iterations: 0 of 600 [13:00:54] Finished [13:00:54] [SPG] Native chi angles stored [13:00:55] [SPG] Rotamers read [13:00:55] [SPG] Starting genetic algorithm [13:03:13] [SPG] seed: 132 [13:03:13] [SPG] Designing protein sequence 1 of 30 [13:09:27] [SPG] 10.0 % [13:15:33] [SPG] 20.0 % [13:27:00] [SPG] 30.0 % [13:46:31] [SPG] 40.0 % [14:10:13] [SPG] 50.0 % [14:17:53] [SPG] 60.0 % [14:36:28] [SPG] 70.0 % [14:42:16] [SPG] 80.0 % [14:48:05] [SPG] 90.0 % [14:53:56] [SPG] 100.0 % [14:53:56] [SPG] Writing current.xyz [14:53:56] [SPG] Sequence 1 completed: [14:53:56] VTMETTYSKEISKLJJRIKFJKVGLEAMAQVLMSYETYKRYLERAGSZES . . . [14:53:57] Iterations: 20 of 600 [14:53:58] Finished [14:53:58] [SPG] seed: 264 [14:53:58] [SPG] Designing protein sequence 2 of 30 [15:01:08] [SPG] 10.0 % [15:08:01] [SPG] 20.0 % [15:14:37] [SPG] 30.0 % [15:21:15] [SPG] 40.0 % [15:27:38] [SPG] 50.0 % [15:33:31] [SPG] 60.0 % [15:39:10] [SPG] 70.0 % [15:44:54] [SPG] 80.0 % [15:50:34] [SPG] 90.0 % [15:56:35] [SPG] 100.0 % [15:56:35] [SPG] Writing current.xyz [15:56:35] [SPG] Sequence 2 completed: [15:56:35] IDLPNEKKKLLQKFLKQVNITDAGMRAMAIVLJNLREMLKYLQELGKLEE . . . [15:56:35] Iterations: 40 of 600 [15:56:36] Finished [15:56:36] [SPG] seed: 396 [15:56:36] [SPG] Designing protein sequence 3 of 30
I hadn't seen this before and thought it looked interesting. Seems like the client is actually designing a protein instead of trying to see how one folds...
     
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Join Date: May 2000
Location: California
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Dec 2, 2003, 07:46 PM
 
FahCore_ca is the Genome core. It is available on x86, but they have been foot dragging about compiling it for Mac.

If I remember correctly, the FahCore_ca source code is in Fortran, and they have had compile problems with Mac Fortran compilers.
     
   
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