It's basically the same ole same ole, "we are not currently releasing a Mac version but are open to it in the future" schpeel with DDO.
I'm not sure yet what to make of this game. From the looks of things, it will be yet another slow, methodical level grind type of MMO, with no plans for pvp of any kind which quite possibly might kill the game before it releases. And the reason they decided to not implement pvp is b/c they are pushing for a quick launch and don't want to take the time required to somewhat balance classes b/c they want quick bucks 1st.
Who knows though, it may turn out to be incredible, but I don't have my hopes up right now.