Yep, I just experienced this AGAIN, and now it is getting old.
I have a very clean 10.3.2 system, I run Cocktail weekly, etc.
I am writing this response in Explorer! Go figure! I don't know what the hell is wrong.
iChat works, Mail works, etc, but NO Safari. The little progress spinners just keep spinning, with no page loading.
At first I thought it was my Airport Extreme, but the fact that other stuff works is puzzling. I quit Safari, dumped the cache, etc. What is going on?
Wierd!