It should work okay. My Current Kodak Camera is not listed in the iPhoto Compatible list but it comes up. I'm on my third Kodak Camera(I keep upgrading 'cause I like them,) I'm using the 6490 with the PrinterDock. If you do get the DX 4350 and iPhoto doesn't see it, using the EasyShare system or a printer dock will solve the problem. iPhoto will see them. And if that oesn't work you can use the Kodak EasyShare Software and export to iPhoto. Either way the Kodak Camera will work with your Apple.