As I understand it, Tiger doesn't actually make any changes to the filesystem itself: Spotlight stores its metadata in ordinary (though hidden) files. As such, it should be safe to run DiskWarrior on such files. You may need to rebuild or re-index your metadata afterwards (if such an operation exists), but the filesystem itself should not break. This is inconvenient, but hardly fatal.
This is similar to the what happened with 10.2.3, which introduced HFS Journaled. DiskWarrior would work with this, but it would deactivate Journaling in the process; you had to activate it again afterwards. When DiskWarrior was updated for OSX, this was fixed.
My guess is that an update will follow soon after Tiger, fixing this inconvenience. In the meantime, however, it is unlikely that there will be any problems with using it.
WARNING: I'm not a Tiger developer, nor do I have Tiger by any other means. This is just what I can figure out from what they've said publicly, coupled with how they've worked with HFS+ in the past. I could, in theory, be wrong.