The only reason I use Explorer anymore is because it's the only browser I know of that can do just that. I have it set so when I click on a Jpeg on a web-page, it automatically opens in Preview, while saving it to the desired download folder.
With Safari and Netscape, it keeps opening the Jpeg in a new window!
That said, with the in-app mail featur, I still regard Netscape as the best browser out there.
(I think Mail is stupid compared to Netscape!)