I like Safari Stand and Safari Block. Safari Block blocks ads. In fact, it has a subscription to Easylist like Adblock Plus for Firefox, and you can also add your own personal block list to it. Safari Stand allows you to prevent plugin items from loading, and then load them individually later if you wish, sort of like Flashblock for Firefox. The only thing is, it blocks other plugins besides Flash. Safari Stand can also block favicons, which I really dislike, disable resizing of the window, stop junk messages from being printed in the status bar, and has several other options.