I'm pretty comfortable with either, at work fireworks is what we use, but for contract stuff (i.e. when I have a choice) I'll take imageready any day. "jumping" back and forth between photoshop is a great thing, I also prefer its batch processing tools (which whup up on fireworks any day of the week), and its support for adobe program file types (i.e. illustrator v. whatever) rawks. but I have a preference for adobe as opposed to MM so, maybe that makes me biased.