I wouldn't think so but why are you transferring via itunes? If you mean that you are playing files in itunes from a card I still don't think you would have stuttering but it might depend on the audio you have.
USB 1 is 12Mbps=1.5MBytes/second max
AIFF bitrates aren't that high (1.4Mbps=175KBytes/sec).
However, if you are doing stuff in the background like downloading from the internet, basically anything that needs disk access or cpu, it might stutter.
If you are importing from the card while playing it, it might be more likely to stutter as you are doing more things at once. MP3 encoding uses a fair bit of processing power.
Check that your device doesn't have bad drivers. I had an old floppy drive that took minutes to transfer data.