I can think only of this:
(1) Move your entire ~/Library/Preferences folder to the desktop.
(2) Try Limewire, should work now. Quit it.
(3) Move a group of preference files from the old "Preferences" folder on the desktop to an automatically created new "Preferences" folder in ~/Library. Test Limewire again, if OK, then quit it and
(4) Continue repeating (3) until you identify a group of pref. files that breaks Limewire. After this,
(5) Test pref. files from this culprit group of pref. files one by one. Delete this pref. file.
Tedious, but the only one way I can think of now.