Intuit has already said Quicken 2007 won't work with Lion. After trying some other Mac software, I have decided to go with running Quicken on a Windows virtual machine. Am waiting for Windows to arrive by mail, in fact.
However, I have some other older software. How the heck do you know if they'll work or not? One is InTouch With, by Prairie Group software, which I've used for more than 10 years, easily. I've emailed the company but don't have an answer yet. I have an older version of InDesign, as well. Is there a list somewhere? Definitely won't be upgrading to Lion until I know whether some of this stuff will work or not. I hardly ever use InDesign, so that is not a deal-breaker... I got it for a project several years ago which I no longer do.