This is a very unscientific method, but it has actually worked for me in the past. I take absolutely no responsibility for any damage you may do to your computer by taking this advice.
1. Turn your computer off.
2. Place your thumb in a soft cloth, like a cotton washcloth.
3. Grasp the screen with your free hand and gently rub the area where the pixel anomaly is occurring with your thumb. Don't press too hard -- just massage gently. Do this for about 5 seconds or so.
4. Turn your computer back on.
If this doesn't work, the pixel is just blown and there's nothing that I know of that you can do to fix it. Sorry.
![Frown](http://forums.macnn.com/images/smilies/oldschool/frown.gif)