[booshi]

I just got a new PowerBook from Apple, because my old one had a lot of problems with white spots.

Now, on my new PB, after I set preferences for all of my Apps (Safari, Fire, Mail, and even Mac OS X in general) none of them stay. They save and then a few hours later, they're gone.

I'm installing the OS update right now, will that fix it? If not, what will?

[CharlesS]

Check that you have write access to the Preferences folder.

Try running a permissions repair in Disk Utility.

[bradoesch]

I have this problem when my hard drive has less than 1-1.5 GB free space. Doesn't sound like you've had that much time to fill up the drive though.