For those with older or low end Macs, an interest in protein related projects, or just a dislike of the large work units being offered by SETI, Einstein and World Community Grid, SIMAP has released a beta for 10.3.9 and above - both PPC and Intel CPU's.
While it is not perfect yet, they do seem to be quite responsive to the issues that have come up. Could also be an opportunity for Team MacNN to get a jump on other Mac teams.
SIMAP