The Lattice Project
They have applications for OSX (both PPC and Intel!), Win32 and Linux32. Come on aboard!
Research:
Here are some of the projects and analyses being run on Lattice.
The Edwards laboratory is using the HMMPfam service to compute Pfam assignments for all bacterial, plasmid, and virus protein sequences from Swiss-Prot, TrEMBL, GenBank, RefSeq, and TIGR's CMR, plus an inclusive set of all plausible Glimmer predictions from RefSeq bacterial genomes. These protein sequences, and their Pfam assignments, are used in the Rapid Microorganism Identification Database (
www.RMIDb.org). The HMMPfam service is also being used as a model for "data-heavy" bioinformatics applications on the Lattice Grid infrastructure, a collaboration between the Cummings and Edwards laboratories.
The Cummings Laboratory is using gsi to assess the performance of the statistic in a variety of situations.
Maile Neel and Joanna Grand are using Marxan to quantify the effects of poor and incomplete data on the ability to capture biological diversity in nature reserves.
The Laboratory of David Fushman is running protein
rotein docking algorithms on Lattice. When driven by experimentally derived constraints, these will help in modeling the structures of large multi-subunit proteins, and the interactions of such proteins with various ligands. CNS is the featured Grid service in this project.
Floyd Reed and Holly Mortensen from the Laboratory of Sarah Tishkoff have run a number of MDIV and IM simulations through The Lattice Project. These are studies in molecular population genetics that seek to use DNA sequence polymorphism to estimate the times of divergence and migration rates among ethnically diverse human populations in Africa.
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